Clinical Trial Navigation
A step-by-step guide to finding, evaluating, and enrolling in clinical trials matched to your cancer type and molecular profile.
Collect your pathology report, genomic profiling results (FoundationOne, Tempus, Guardant), and any IHC/FISH results. Key data: cancer type, stage, mutations, TMB, MSI status, PD-L1.
Use advanced search filters: condition, intervention type, molecular markers, phase, and location. Focus on Phase II/III trials with your specific biomarker in the eligibility criteria.
ClinicalTrials.gov →Programs like NCI-MATCH, TAPUR, and My Cancer Genome match patients to trials based on molecular alterations — regardless of cancer type (tumor-agnostic).
NCI-MATCH →Key questions: What phase is it? Is there a placebo arm? What are the eligibility criteria? What are the known side effects? Will travel be required? Is there a safety lead-in?
Contact the trial coordinator listed on ClinicalTrials.gov. Ask about screening requirements, insurance coverage, and whether your current treatments affect eligibility.
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